Center for Food Safety, the Center for Biological Diversity, and Pesticide Action & Agroecology Network North America have sued the Trump administration over the registration of trifludimoxazin, a potent PFAS pesticide that breaks down into long-lived, PFAS byproducts.

PFAS, or perfluoroalkyl and polyfluoroalkyl substances, are a class of chemicals characterized by ultra-strong carbon-fluorine bonds that are highly resistant to break down. Trifludimoxazin takes years to decades to break down. The groups’ lawsuit was filed Friday in the 9th U.S. Circuit Court of Appeals.

The Environmental Protection Agency has approved the use of trifludimoxazin on many crops, including corn, wheat, oats, soybeans, oranges, apples, peanuts and almonds, despite acknowledging the chemical’s potential harms to wildlife and human health.

“Trifludimoxazin is a likely human carcinogen that belongs to a family of weedkillers that also causes reproductive harm, birth defects and neurological deficits in animal studies,” said Bill Freese, science director at Center for Food Safety. “As if the health threats weren’t enough, this incredibly potent herbicide can drift to stunt crops and wild plants hundreds of yards from a sprayed field, while runoff threatens wetland plants. Potent biocides like this have no business on the American landscape.”

The EPA acknowledges that trifludimoxazin causes thyroid tumors in rodent studies but did not assess the cancer risk to farmworkers who use the pesticide or to people exposed to trifludimoxazin-contaminated food or water.

Spray drift is likely to result in widespread harm to native plants and crops grown for food. Trifludimoxazin is 10 times more toxic to plants than dicamba, the herbicide whose rampant drift and runoff has caused unprecedented damage across many millions of acres of crops since 2017.

“While everyone’s distracted by the Trump administration’s erratic actions on the world stage, it keeps approving dangerous forever pesticides right here on our own soil,” said Nathan Donley, environmental health science director at the Center for Biological Diversity. “It’s unconscionable, immoral and illegal. Our kids and grandkids deserve better than to be saddled with pollution that never goes away.”

“Continuing to register new herbicides like trifludimoxazin keeps farmers on the pesticide treadmill and perpetuates the problem of herbicide resistance in weeds,” said Emily Marquez, Ph.D, staff scientist with Petitioner Pesticide Action & Agroecology Network North America. “The potential for PFAS pesticides to contaminate water and soil wherever they are used is highly concerning for the health and livelihoods of people in farming communities.”

Trifludimoxazin is one of many currently registered herbicides that kill plants by shutting down an enzyme (protoporpyhyrinogen oxidase, or PPO) that is also present in people. Even though animal research demonstrates these “PPO inhibitors” have common adverse effects on the liver and cause birth defects in fetuses exposed in utero, the EPA has refused to conduct a cumulative risk assessment of trifludimoxazin and other PPO inhibitors as required by law. This is especially concerning because two of the products approved by the EPA contain trifludimoxazin combined with saflufenacil, a second PPO inhibitor, meaning simultaneous exposure to both for workers.

Background

Trifludimoxazin was originally approved by the EPA in 2021 for nationwide use on corn, soy, fruit and nut crops. Center for Food Safety and the Center for Biological Diversity sued, saying this approval violated the federal Insecticide, Fungicide, and Rodenticide Act and the Endangered Species Act. That lawsuit noted the EPA’s finding that the herbicide had the potential to cause cancer, and that it would “likely cause severe harm" to many threatened and endangered fish, including endangered populations of Chinook salmon and steelhead trout, Atlantic sturgeon and smalltooth sawfish.

In response to the lawsuit, the pesticide company voluntarily agreed to stop the manufacture and sale of the pesticide in 2022. Despite these harms, Trump’s EPA proposed registering trifludimoxazin again for widespread use in 2025 and issued the approval in June 2026. Trifludimoxazin is the fifth PFAS pesticide approved under the second Trump administration.

More insane idiocy from the petty huckster clown king whose idea of governance is threatening lawsuits, trade wars, buildings that won't put his name on them; bungling war and peace; flaunting Nazi loyalty queries and sadistic images of black men in chains; and distracting from it all with the dumbass geographic circlejerk of inventing “LAKe AMeRiCA.” The Internet was born for this: Cue Donald Ducks, the Straits of Our Moose, Lake Dead Pedo Bestie, Lake Superior President Obama, and Lake Stupid Fucking Moron.

Last week, after God killed the wrong 80-year-old in the 784th year of a presidency that feels like "being in middle school when there's a substitute teacher and a student has a medical emergency," yet more banal slop issued from a needy racist sociopath so stupid he once seemingly conflated the Very Hard words "transistor" and "transgender" to claim Biden's CHIPS Act offered billions to domestic tech companies but "if you weren't transgender, (you) didn't qualify." Jesus. No wonder, à propos of nothing, the widely deemed "worst president in U.S. history" took time out from his busy mob boss schedule to declare himself the bestest - take that Honest Abe - after his faithful Human Printer dug up a similar 1948 Life Magazine chart, which is "exactly the kind of thing a healthy, high-functioning person shares."

Other things he did, abetted by a confederacy of dunces, stooges, techno-fascists, warmongers, crypto dorks, "unfuckable hate nerds" and "an actual Jewish Nazi": Having hit the six-month mark of his Iran debacle, he giddily proclaimed, "Mission Accomplished!" despite a. the only thing achieved is handing a newly empowered Iran control of the Strait of Hormuz as U.S. gas prices skyrocket and the economy implodes, b. he evidently missed the part where George W's 2003 banner aboard an aircraft carrier became a queasy punchline, c. he did so amidst reports his and Kegsbreath's said debacle has pushed the US military into a "beyond critical" shortage of money and missile interceptors in the case of an enemy attack, forcing them to shift funds around "in imaginative ways" - because everything he touches dies and we probably will too.

A fragile child, he demands fealty to even his ceaseless clusterfucks. Thus the latest inane authoritarian hokum from a Department of Homeland (sic) Security that alas hasn’t lost any of its fascist fervor since the brutal puppy-killing days of ICE Barbie. Its new, dystopian, “genuinely deranged” missive: A glowering image of Dear Dumb Leader with the dark challenge, “Did you remain loyal?”, which chillingly fails to consider just what atrocities they’re demanding allegiance to. The answer came in a post that swiftly followed: Sadistic footage of shackled Haitian immigrants, targeted after losing Temporary Protected Status for no reason but mindless, racist cruelty, being shuffled onto planes in pouring rain to the sneering tune of a Creole song about returning home - complete with fawning close-ups of the chains on their feet. Well done, sick fucks.

Meanwhile, the trail of destruction goes on apace. In D.C., after the East Wing and reflecting pool - we like the meme of him studying it with, "All I see is scum" and a lackey saying, "Well, it is a reflecting pool, sir" - we've reached the mobsters' "offer-they- can't-refuse" phase on the besieged Kennedy Center. Having repeatedly lost in court, the regime now threatens to demolish the not-long-ago-flourishing Center unless a tantrum-throwing 10-year-old gets his name "prominently added" to its exterior with "appropriate respect" of his efforts to "save” it from a fictional "death spiral" that's rendered it "dilapidated, outdated, decrepit and embarrassing to the Nation’s Capital," which is some pot/kettle. If they can't plaster his ghastly name over it - inscription, plaza et al - they'll replace it with "an outdoor amphitheater," aka a lawn.

They're also pushing to sell off part of Yosemite National Park, like everything else, to the highest bidder, though the seller is such an imbecile he still cringingly says "Yo, Semites!" He's such a petty dolt he's also skipping this year's 9/11 remembrance at Ground Zero because he wasn't allowed to give a Nazi speech there, opting to give it at the Pentagon before rushing off to the Irish Open at his crappy golf course, 'cause priorities. Having trashed jobs, health insurance, food aid, the environment and most of our global alliances, he blew up trade talks with Canada, calling its endlessly nice residents "nasty people," and holding a clownish Oval Office event to sign an idiotic executive order renaming Lake Ontario to “LAKe AMeRiCA,” which he's "been thinking about for a long time" with what's left of his tiny brain. (Here he is on trade: The stupid, it burns.)

"All it takes is a good pen and some intelligence,” he said, only batting one for two in a pretend-name-changing event labeled, "Making the Great Lakes Even Greater.” Then - what a feckin’ playacting infant - he drew a line through the doomed lake and intoned, “We have notified various people who needed to be notified...This is official.” He said he’d instructed craven lickspittle and Interior Secretary Doug Burgum to "take all appropriate actions." Burgum slavishly wrote, “We’re on it, Mr. President!”, thus becoming the only person on Planet Earth to take this puerile claptrap seriously, evidently unaware an executive order is not a law and every ship entering the Great Lakes has to go through Canada's Welland Canal, including $26 billion in U.S. trade, and it would be a shame if Canada up and supersized their tolls, and thank you for your attention to this matter.

Uncle Bernie and most of America promptly responded they'd rather have affordable health care, thanks, also housing, food, education and cancer research. Nova Scotia's Conservative premier Tim Houston, "not exactly a firebrand," opined, “We’re into some real foolishness now. It’s Lake Ontario, buddy." Canada's newly combative Prime Minister Mark Carney, out of fucks to give, noted that long before Europeans came the lake was named by Native Americans using the Huron word "Ontari’io," for, "The lake is beautiful, the lake is big." "The name is more than 400 years old," he said. "Canadians know that naming reality means calling it Lake Ontario - then, now and always." The Canadian Resistance Army, who earlier defended penguins, also chimed in, declaring, "We're going to trade war/Beavers and moose won't take it any more."

Above all, it was agreed, “LAKe AMeRiCA" is what God invented the Internet for. The names spooled out in a gleeful torrent.

Lake Release the Epstein Files. Lake Gulf of Mexico. Lake Are We Doing This Again. Lake Micropenis. Lake Natalie. Lake Huron Thin Ice with Melania. Lake Universal Healthcare. Lake Eerily Overweight Pres Dick J. McRectum. Lake Felon. Lake Not Eerie. Lake Oh Canada. Lake Small Dick Energy. Many chose Lake Obama. Wisconsin Gov. Tony Evers created the politically incorrect Lake Retard: "See, I can sign napkins that say things too." One decided to "just keep calling it Lake Epstein, like the Founders wanted." Mapquest, unlike cowering Google, not only declined to change the lake's name but invited viewers to "spread some geographic joy" and "name it whatever you want." One result: Lake Who Uses Mapquest Anymore.

Many noted the traditional Great Lakes litany of "H.O.M.E.S" had entirely logically become "S.H.A.M.E." People renamed their toilet bowl to Lake Trump. The White House to Home of Diaper Butt. Mar-a-Lago to Poopy Pants Palace. The United States of America to the Epstein States of Pedophiles, or just South Canada. President Trump to President Dickhead. California to Amerifornia. Strait of Hormuz to Strait of Our Moose. People mocked his thieving choice of one of the smallest and dirtiest Great Lakes. They noted, "Nobody in Ontario gives a single solitary fuck what Assclown McCrappy-Pants says about anything." They griped the name change "really screws with the lyrics of Wreck of the Edmund Fitzgerald."

"What are they trying to distract us from this time?" they asked. Response: "The previous distraction." Some coddled the needy child-king: "Good for you, li'l fella." Some railed: "Jesus Christ, can somebody just get him a coloring book already?" Some were still baffled by how low we've gone: "Wait, this is real?" Some refused to go there: "Nope." Some summoned the great Talking Heads: "As things fell apart/Nobody paid much attention." And some fought back against the incessant bullying. After the Center for American Progress released a report finding billions spent on ICE thugs and National Guard swarms had no real effect on reducing violent crime, Trump threatened a $5 billion lawsuit if they didn't retract it. The center stood firm against "a transparent attempt to silence us." "We will neither cower nor bend in the face of it," they said. And, still and all, we will snark away.

Update: Talk about "Do not obey in advance": After defying the petty madness, usage of Mapquest has surged to about 50 times its usual rate, leapfrogging past Google and Apple Maps to become the most-downloaded mapping app, and the fourth most popular of all apps excluding games in the US. Along with their "spread some geographic joy" invite, they posted a mocking, all-caps retort: "OUR MAPS ARE BIG AND BEAUTIFUL. PEOPLE COME UP TO US AND SAY WE'LL GET THEM PLACES. AND WE DO!!" Lol.

Canada vs. the Epstein Statesof AmericaImage from Bluesky