In this edition: Bad medicine, imperfect sound forever, know when to fold ’em, brainiacs, and a call of the wild.

Scientists are growing miniature human brains in labs around the world. (Yep, you read that right.) For Wired, Claire L. Evans reports on the latest research in the field of organoid intelligence, or OI, where scientists are artificially growing brain organoids from tiny human samples, whether skin, blood, teeth, or even hair. As these seed-sized globs mature, they are able to send and receive electrical signals, and even learn to remember and anticipate them. In other words, this living matter is programmable. “And this is where things get truly weird,” writes Evans.

For now, these neural computers are mostly of interest to researchers who want to work with neurons without taking on the tedious wet-lab husbandry themselves. Eventually, however, the company hopes that neurons will prove themselves to be an energy-efficient, resilient substrate for more general computing applications—including some tasks currently handled by AI, like image recognition and classification.

“When you think about what you want from AI, it’s biology,” said Brett Kagan, Cortical Labs’ chief operating officer, when I reached him over Zoom. “You want it to be self-repairing as much as possible. You want it to be adaptable. You want it to be long-lived. You want it to be energy-efficient. These are all features you get for free in biology.”

Midway through Boyce Upholt’s mind-boggling dispatch, one of his sources sums up the central challenge of the Gulf Coast canid: “Why is there not just a simple explanation for what this thing is?” The “wolfy coyotes” of southeastern Texas hold genetic traces that may link them to red wolves, which were declared extinct in the wild in 1980. But a lack of data makes it challenging to define the species—or, for that matter, to determine whether a private company has cloned the red wolf or something else entirely. Upholt doesn’t deal in simple explanations; the pleasure, here, is in the complexity.

The concept of a “species” is less sturdy than your high school biology teacher might have led you to believe. The most familiar definition is that a species consists of animals that can produce fertile offspring. But that’s a rule various species of canids violate all the time; it’s long been clear that North America’s soup of Canis genes is something less like a family tree and more like a river—one that’s broken by islands and sandbars into many braided channels that split and merge and re-split.

Travis Diehl’s feature on “Star Axis,” the half-century project of artist Charles Ross, is transportive, an ideal combination of explanatory and sensory writing. Not all of us will make it to the sparse section of Anton Chico, New Mexico, to ascend the steps of Ross’s pyramid and see the stars reel. For those of us who don’t, Diehl’s piece makes for an elegant consolation prize.

Ross broke ground during the U.S. Bicentennial year. Fifty years and more than $10 million later, he says “Star Axis” will be done by winter. In the final design, the staircase rises 11 stories through a tunnel blasted in the rock of Chupinas Mesa, 6,000 feet above sea level and into a viewing chamber in a concrete, stone and steel pyramid 52 feet tall. A circular window there frames Polaris. As viewers climb each of the 147 stairs, the rim of the window appears to broaden, giving an idea of how far Polaris has and will move in a given amount of time, during the 26,000-year cycle known as precession, the gravitational wobble of the Earth’s rotational axis.