Lies are Unbekoming | September 24, 2026
The label for Humira, once the best-selling drug in the world, lists its risks in plain print. One of them, in the label’s own words, is new “autoimmune” disease.
A drug prescribed for a condition labelled autoimmune carries a warning that it can cause a condition labelled autoimmune. That contradiction sits in every box, on a folded paper almost nobody reads.
My new book starts there.
No Autoimmunity: The Body Doesn’t Attack Itself
For seventy years, “your body is attacking itself, and we don’t know why” has ended the conversation for people diagnosed with multiple sclerosis, lupus, rheumatoid arthritis, Hashimoto’s, Type 1 diabetes, Crohn’s and psoriasis. More than eighty conditions now carry the autoimmune label. The diagnosis comes with a prescription for life. It almost never comes with a question about cause.
This book asks the question and answers it from the framework’s own records: its drug labels, its journals, its regulatory filings, and its own experiments.
What’s inside
Humira: The Cover Story. A drug that once earned more than twenty billion dollars a year, whose own label warns of lymphoma and new conditions labelled autoimmune. Stop taking it and the symptoms usually return, so the prescription never ends.
The Autoimmune Label. In 1956 researchers produced thyroid disease in rabbits by injecting thyroid tissue with a powerful adjuvant. A category defined by “unknown cause” has since grown to more than eighty conditions.
The Three Deceptions. The “immune system” as an army, antibodies as soldiers, autoimmunity as the army turning on itself. Each idea props up the others.
Richet’s Erased Nobel. The 1913 Nobel Prize for showing that injected foreign proteins sensitise the body. Medicine kept the prize and filed the warning under “allergy.”
The Nervous System. The 1976 swine flu campaign and the paralysis cases that followed. Hal Huggins removed mercury fillings from MS patients, documented their improvement, and lost his licence.
The Endocrine System. Fluoride and bromide crowding out iodine, and a lifelong thyroid pill that ensures nobody learns whether the gland could recover.
Connective Tissue. Evelyn Hess’s catalog of more than seventy medications that produce lupus and related disease, which usually clears once the drug is stopped. The book’s central proof, from the framework’s own literature.
The GI Tract. Celiac disease went from one child in five thousand in 1950 to about one person in a hundred today. The chapter covers what changed in the food.
Skin and Blood. Psoriasis appears where skin is injured, and the drugs sold for psoriasis are documented to cause it.
The Documented Reversals. Drugs withdrawn, mercury removed, implants taken out, diets changed. Once the injury is gone, the body mends.
What Made the Reversal Possible. Remove the harm, restore what the body needs, give it time, and protect what still works.
How to Think About the Diagnosis You Were Given. Written directly to the reader holding a diagnosis, with the exposure history to build and the questions to ask.
Where to Go from Here. A reading list and the kinds of practitioners worth finding.
Every chapter closes with How to Explain It to a 6 Year Old, a plain-language section you can read aloud to a child or hand to a relative who will never read a medical paper. The book also includes a glossary, a bibliography of more than 100 sources and a full index.
Who this book is for
If you or someone you love has been handed one of these diagnoses, read this before accepting that the answer is a lifetime prescription. If you’re a practitioner, or someone who simply wants to check the record, the full documentary trail is here, referenced source by source.
288 pages, paperback.
The shelf
No Autoimmunity joins the rest of the Unbekoming catalogue at lulu.com/spotlight/unbekoming.
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In 1792 Paris, a “north-going astronomer,” Jean-Baptiste-Joseph Delambre, set forth for Dunkerque, France, while a “south-going astronomer,” Pierre-François-André Méchain, made his way to Barcelona, Spain. As leaders of the meridian expedition, their modest ambition was to measure the world. They would use a new measure to be called the meter. “The meter would be eternal because it had been taken from the earth, which was itself eternal. And the meter would belong equally to all the people of the world, just as the earth belonged equally to them all.”
If a nonfiction book opens with a map and a list of dramatis personae, make some coffee and settle in. Such is the case with historian Ken Alder’s The Measure of All Things: The Seven-Year Odyssey and Hidden Error that Transformed the World—the story of the birth of the metric system amid the ferment of the French Revolution. It’s a thriller.
We start with our bodies, measuring height and weight and life. We want to know what health is, what beauty and pain and performance look like. We weigh our brains for intelligence, ability, sickness, happiness. We fight about race and politics, sex and money, images and words. We stalk the planet, its history and geography, biology and chemistry. We wrestle with space-time, its mathematics and paradoxes. We have no idea what to do about consciousness. And then there’s the small matter of love. We are obsessed and we cannot stop.
At its heart, measurement is a utopian undertaking, one that aims to make perfect sense of the world. But at every turn, it runs up against the real world, and every so often, our understanding of reality itself. We know that the act of measuring changes what is measured. Might it be changing us measurers, too?
Welcome to a reading list about measurement—not only as techne, art or craft, but as episteme, knowledge, its conquests and collapses, and what it really gives and takes away.
“In 1730, the influential physician Bernard Mandeville recalled a patient asking his doctor whether he was tired of hearing ‘so tedious a Tale’ of pain. His physician gently murmured: ‘Your Story is so diverting that I take abundance of delight in it, and your Ingenious way of telling it, gives me a greater insight into your Distemper, than you imagine.’” Now if you can get a doctor to listen to you for five undistracted minutes, count yourself lucky. Joanna Bourke takes stock of pain and its vocabulary for Aeon: “Our Anaesthetic Times.”
Indian kids tended to be small, curious, energetic as babies, growing up lean, active, rudely healthy. (I use the past tense because I’m not sure whether this is as true now as it was when I was little.) And yet, our parents thought us skinny and tried to feed us all the time. Was that a normal parental thing for the times, and if not, where did they get the idea that something needed to be fixed?
Universal standards have a way of making us feel competent and good, like, get your blood pressure down to 120/80 and you’ll be all right. But as Singh, a Harvard-trained anthropologist, points out: “Pretending that differences don’t exist doesn’t make them disappear; it only drives practitioners to rely on flawed intuitions.”
Citing case after case of medical benchmarks—too little, too much, too sideways—across the world, Singh calls for a system altogether more nuanced and considerate than the current “myth of the universal patient”—something that won’t cause actual harm, something that will help us see the real humans behind the data.
When my daughter was ten-and-a-half months old, she qualified as “wasted,” which unicef describes as “the most immediate, visible and life-threatening form of malnutrition.” My wife and I had been trying hard to keep her weight up, and the classification felt like a pronouncement of failure. Her birth weight had been on the lower end of the scale but nothing alarming: six pounds, two ounces. She appeared as a dot on a chart in which colored curves traced optimal growth; fifteenth percentile, we were told. She took well to breast-feeding and, within a month, had jumped to the twentieth percentile, then to the twenty-sixth. We proudly anticipated that her numbers would steadily climb. Then she fell behind again. At four months, she was in the twelfth percentile. At nine-and-a-half, she was below the fifth.
Our pediatrician was worried. Ease off the lentils and vegetable smoothies, we were warned; we needed to get more calories into our babe. Ghee, peanut butter—we were to drench her food in these and other fats and wash them down with breast milk and formula. And that’s what we did. When we came back a month later, though, we learned that she had dropped further—and crossed into “wasted” territory.
“There are two kinds of people in the world: people who think there are two kinds of people in the world and people who don’t.” Science or self-help? Louis Menand assesses “society’s people-sorting operations” for The New Yorker: “What Personality Tests Really Deliver.”
Have you ever taken an IQ test? How about an aptitude test for studies or a psychometric test for work? How about an online quiz?
“You were supposed to be there already. Didn’t the tests show you had a head start?” Svoboda, labelled a “gifted” child in the ’80s and dealing with its fallout in her adult life, unpacks the deeply problematic, yet starry, history of testing. She looks at Stanford-Binet, Army Alpha, SAT, and others—all ways to measure human potential. Intelligence and aptitude tests, “binary stars circling in the same orbit,” Svoboda says, seem to be asking and answering: Who deserves a chance, and who doesn’t? Who is worthy, and who isn’t?
For the American psychologist Lewis Terman, who devised the Stanford-Binet IQ test, the birth of a gifted child was like the birth of a star. In the name of illuminating what he saw as a void, Terman sought out the stars that burned brightest. “The school has no more important task than to foster the development of the mentally gifted,” the researcher at Stanford University in California told attendees at a meeting in San Francisco. “Our chances of survival . . . may well depend upon the discovery and utilisation of highly superior abilities of every kind.” To further this mission, Terman urged hundreds of children all over California to sit for his newly developed intelligence test in the 1920s. Intending to prove his theory that high IQs predicted life success, he sorted the highest scorers into a group of 1,521 children (called his “Termites”) that he would follow and document throughout their lives.
“Why Netflix looks like that.” Will Tavlin investigates what goes on behind the scenes at the streaming behemoth for n+1: “Casual Viewing.”
In hydraulics, pumping high-pressure fluid into a well causes rock to crack and oil and gas to come pouring in. This is called fracturing, or fracking. Burnett, a Princeton historian of science and part of a scholar-artist-activist collective called Friends of Attention, has adapted this term to refer to an insidious property of the attention economy. “Fracking eyeballs” refers to applying psychological and advertising techniques under pressure to bait and extract monetary value from human attention. (I don’t know how they live with this mental image all the time, though.)
This essay, opening at a 1925 Harlem shop window with a “puzzling totem face” and crammed with historical anecdote and detail, comes from the magazine’s Issue 04: Measurement. Do check out the whole issue: “How do you measure seeing god? Does testing vaccines need to take so long? Outlining poverty. Asking better questions. The origins of the ad economy. Can we really say how smart AIs are? Domestic violence during lockdown. Sex, drugs, and colonoscopies. Our most pedantic issue yet.”
See also Burnett’s Public Domain Review essay, “Cybernetic Attention,” where he pursues the “pre-history of the laboratory research that has relentlessly worked to slice and dice the attentional powers of human beings.”
In Nixon’s earliest experiments, he would hide in an observation booth, accompanied by a metronome beating half seconds, and then watch closely as two ads were revealed to a seated subject. Ticking his pencil along the rungs of a fascinating little ladder-pad with each beat of the metronome (marking the left side when the eyes were to the left; marking the right side when the eyes were to the right), Nixon created a graphical record of the subject’s visual encounter with the two stimuli.
If you were advertising a car, was it better to show a picture of a car, or of a pretty woman? If one was selling shirt collars, was it better to do so under the headline “Murder!” or the headline “Quality Shirt Collars”? To make a long story short (and to skip over the proto-pataphysical techniques by which Nixon established what we might call a “science of irrelevancy”), Nixon found that “irrelevant illustrations do attract more attention and hold interest longer than do relevant ones.” Which is to say: systematically doing violence to sense raised revenue. This could be proven in his laboratory. Would it be wrong to say that we live, in many respects, in the world evolved from that finding?
“Correlation, one of the most used and least understood concepts in statistics, is easy to mistake for causation because it was made that way intentionally; it’s precisely because of its potential to be misunderstood that it remains so popular. . . . The eugenics movement was built out of correlations.” Read about its history and current state of affairs in this Los Angeles Review of Books essay by Aubrey Clayton for the Legacies of Eugenics series: “The ‘Correlation’ Between Statistics and Eugenics.”
In 1901, Scotland Yard started using fingerprints to solve crime. They weren’t the pioneers. Sherlock Holmes had gotten there first in The Sign of Four, already examining under his magnifying glass, in 1890, what appeared to Dr. Watson as “mere shapeless smudges of dust.” While the fictional Holmes was publishing his fictional monographs in fictional journals, “gentleman scientist” (self-funded and without institutional affiliations) Francis Galton was working on the same thing for real. The era was primed for this kind of work across disciplines and professions—finding and interpreting “clues unnoticed by others.”
And while Holmes was trying to catch bad guys, Galton came up with a malign plan. What if you could use fingerprints as “tiny fossil records, providing evidence of the genealogy, personality, criminality, and perhaps even destiny of individuals and groups”? No more varicolored bad guys, only “a political program of selective breeding to improve, in his view, the human race.”
Empire, race, and “science”—eugenics.
In 1888, a reporter from the Pall Mall Gazette paid a visit to Galton’s Anthropometric Laboratory in London, where instruments developed by Galton measured the physical and mental characteristics—from keenness of hearing to breathing power—of over 10,000 people. The resulting article, titled “A Morning With the Anthropometric Detectives,” described Galton’s laboratory as a world of “order and precision, and tests of the nicest accuracy.” “Dumb though they are,” Galton told the reporter, “what splendid detectives our instruments might prove.” “Splendid detectives!” the reporter exclaimed, “I am not, I hope, in a department of the Criminal Investigation Department, unconsciously yielding convincing proofs of personal identity with some scoundrel hitherto unhung.”
The comparison to detection in the article’s title is no accident: the scientific development of medical and anthropometric instruments like Galton’s coincided with the rise of the detective novel, a genre which, in the words of the literary scholar Ronald Thomas, was “preoccupied with the professional monitoring and identification of bodies.” Fears of mistaken identity and unconscious slips were crystallized in the literature of detection but emerged from a broad range of hermeneutic practices across the era, at a time in which those in power considered the borders of empire and boundaries of racial identity to be insecure.
“Experiments that test physics and philosophy as ‘a single whole’ may be our only route to surefire knowledge about the universe.” Seeing as the lines between them have already been “blurred beyond repair,” here’s another essay by Amanda Gefter for Quanta Magazine: “‘Metaphysical Experiments’ Probe Our Hidden Assumptions About Reality.”
“What happens when you get to the end of things?” This was the question that had held John Wheeler in thrall all his life. A student of Niels Bohr and friend of Albert Einstein who counted Richard Feynman among his own students, Wheeler was a rare soul—a below-the-radar legend, a “physicist’s physicist” who really wanted physics for the people. And throughout his storied career, he kept journals.
We learned in school that gravity is a force that pulls objects together.
Einstein’s theory of general relativity came along and said, well, it’s actually that matter and energy can curve space-time, and that curving is gravity. Wheeler wondered, what if gravity could act on itself, endlessly contorting space-time, and that was what matter itself was . . . warped space-time? But reality had a problem. “The fabric of space-time, at its smallest scales, was loosely woven, chewed by moths, too flimsy to bear the weight of the world. Yet here is the universe. It must be made of something.” What?
A clue: At the end of Alder’s meter book, he quotes Protagoras, a pre-Socratic philosopher: “Man is the measure of all things.”
It dawned on Wheeler that when space and time went, taking the rest of physics with them, there was something left. “With law going and chaos arriving, one principle remains,” Wheeler wrote. “The quantum principle.” Quantum mechanics, he wrote, “destroys the concept of the world as ‘sitting out there,’ with the observer safely separated from it by a 20 centimeter slab of plate glass. Even to observe so miniscule an object as an electron, he must shatter the glass. He must reach in. . . . The universe will never afterwards be the same. To describe what has happened, one has to cross out that old word ‘observer’ and put in its place the new word ‘participator.’ In some strange sense the universe is a participatory universe.”
It was officially the wildest idea he’d had yet. A universe made not of matter, not of space-time, not of stuff at all, but of our choices. It wasn’t what he’d hoped to find; the physics had led him there. He’d pried up space-time, peered beneath, and found himself staring, to his bewilderment, at a mirror. “One finds himself in desperation asking if the structure, rather than terminating in some smallest object or in some most basic field, or going on and on, does not lead back in the end to the observer.”
“The hard problem of consciousness is a distraction from the real one.” For a clearer picture of the fundamentals according to Seth, read his earlier essay for Aeon: “The Real Problem.”
Decades ago, the philosopher David Chalmers came up with a distinction that has since become a popular touchstone in consciousness circles—the easy problem vs. the hard problem. The “easy problem” deals with the physical brain and how its functions and processes create perception, cognition, behavior, etc. The “hard problem” is why such phenomena should be connected to internal, subjective consciousness in the first place. This “explanatory gap” takes a scientific problem into the realm of philosophy. In the sidenote essay, Seth sidesteps the hard problem for what he calls the “real problem”—accounting for “the properties of consciousness in terms of biological mechanisms.” Measuring consciousness, in effect.
In the 10 years that separate the two essays, much has happened, the main event being the astonishing evolution of artificial intelligence. And now we have an unreal problem. In this Berggruen Prize-winning essay, the neuroscientist discusses the possibility of consciousness in AI. But as he says: “The future history of AI is not yet written.”
Intelligence and consciousness are different things. Intelligence is mainly about doing: solving a crossword puzzle, assembling some furniture, navigating a tricky family situation, walking to the shop—all involve intelligent behavior of some kind. A useful general definition of intelligence is the ability to achieve complex goals by flexible means. There are many other definitions out there, but they all emphasize the functional capacities of a system: the ability to transform inputs into outputs, to get things done.
Consciousness, in contrast to intelligence, is mostly about being. Half a century ago, the philosopher Thomas Nagel famously offered that “an organism has conscious mental states if and only if there is something it is like to be that organism.” Consciousness is the difference between normal wakefulness and the oblivion of deep general anesthesia. It is the experiential aspect of brain function and especially of perception: the colors, shapes, tastes, emotions, thoughts and more, that give our lives texture and meaning. The blueness of the sky on a clear day. The bitter tang and headrush of your first coffee.
“In the space between the hands-on, physical reality of experimental science and the structured narratives fit for printed journals, sits a special genre of scientific writing: lab notebooks. They are the closest witness to ‘science in the making.’” Ulkar Aghayeva writes a lavishly illustrated essay for Asimov Press: “A Brief History of Lab Notebooks.”
Chiang points to two sources of inspiration in his story note: “The Electric Ant,” a Philip K. Dick story in which a man visits a doctor, only to be told that he’s a robot, and proceeds to open himself up to look at his own inner workings, and The Emperor’s New Mind, a book by mathematician Roger Penrose, in which a chapter discusses the concept of entropy. He’s struck by Penrose’s notion that we’re “consuming order and generating disorder,” and that we, given the laws of thermodynamics, “live by increasing the disorder of the universe.”
In a young world of mechanical beings where “death is uncommon,” an anatomist performs exquisite auto-dissection—an extreme act of analysis to discover what sustains life and what, therefore, can end it in a “fatal equilibrium.”
This Hugo and Locus-winning story reminds me, in its ending, of something Ursula K. Le Guin says in The Language of the Night: “Only the individual can get up and go to the window, and draw back the curtains, and look out into the dark. Sometimes it takes considerable courage to do that. When you open curtains you don’t know what may be out there in the night. Maybe starlight; maybe dragons; maybe the secret police. Maybe the grace of God; maybe the horror of death. They’re all there. For all of us.”
At first the other anatomists did not believe me when I told them what I had discovered, but in the months that followed my initial auto-dissection, more and more of them became convinced. More examinations of people’s brains were performed, more measurements of atmospheric pressure were taken, and the results were all found to confirm my claims. The background air pressure of our universe was indeed increasing, and slowing our thoughts as a result.
There was widespread panic in the days after the truth first became widely known, as people contemplated for the first time the idea that death was inevitable. Many called for the strict curtailment of activities in order to minimize the thickening of our atmosphere; accusations of wasted air escalated into furious brawls and, in some districts, deaths. It was the shame of having caused these deaths, together with the reminder that it would be many centuries yet before our atmosphere’s pressure became equal to that of the reservoir underground, that caused the panic to subside. We are not sure precisely how many centuries it will take; additional measurements and calculations are being performed and debated. In the meantime, there is much discussion over how we should spend the time that remains to us.
Kanya Kanchana is a writer from India.
Editor: Krista Stevens
Copyeditor: Cheri Lucas Rowlands
At a conformation show, purebred dogs are evaluated by judges according to written documents that strive to capture the exemplary features of each breed. (These standards are searchable via the American Kennel Club; my dog’s breed standard, for instance, is “interested and even mischievous” in expression, but might be faulted for a “short, prancing, or choppy gait.” Noted.) Hannah Berger files a remarkably observed dispatch from one such show in Virginia, where she has traveled to consider show dogs as signifiers, “the ideal against its approximation.” There’s plenty of human folly here, not limited to the interpretation of a “breed standard” and its pursuit over time. A janitor ceaselessly sweeps away dog hair; a mother silences her child as one might a yapping pet. Berger layers her observations into an ending so clever that I gasped.
Now under the jurisdiction of the American Kennel Club in the U.S., conformation shows measure the degree to which a dog “conforms” to its “breed standard,” a document that transmutes historical function into superficially measurable and marketable qualities: proportions, attitude, gaiting patterns. These documents vary widely in length and style. The greyhound’s standard, for example, is a spare two-hundred-word document that strays from sobriety just once in its description of the eyes: “dark, bright, intelligent, indicating spirit.” The standard of the Coton de Tulear, the bichon-like “national dog” of Madagascar, is nearly eight times as long, describing colors and shapes in percentages and angles. Its “joie de vivre” is mentioned twice.
In this story for MIT Technology Review, Sara Harrison explores the field of social robotics and the growing use of robot companions as therapy for autistic and other neurodivergent kids. These playful machines show promise: Research suggests that they can help children practice social skills and offer something overworked therapists and exhausted parents can’t—a patient companion, available 24/7. But Harrison also reports on their limitations and risks. Does this approach truly work? What about all the data gathered on the child? And what happens when a robot friend suddenly stops working and “dies”? A fascinating and unsettling look at tech that has moved into the most intimate corners of a family’s home.
While Moxie found herself in more and more people’s homes, Embodied still struggled to make money. In 2024, the company announced it would cease operations. Its robots—which depended on external servers that the company could no longer pay for—would descend into a deep slumber.
Videos of bereft children who seemed to have become deeply attached to the blue bot began to circulate online. “I don’t want her to leave,” wailed one child in a TikTok video. Desperate parents posted on TikTok, Instagram, and Reddit looking for solutions. “My autistic child is devastated and I’m pissed,” wrote one parent. “Hope Embodied gives us a couple days to say goodbye,” wrote another.
Recommending stories from Emi Nietfeld, Brendan Borrell, Boyce Upholt, Fernando Pinho, and Vann R. Newkirk II.
Midway through Boyce Upholt’s mind-boggling dispatch, one of his sources sums up the central challenge of the Gulf Coast canid: “Why is there not just a simple explanation for what this thing is?” The “wolfy coyotes” of southeastern Texas hold genetic traces that may link them to red wolves, which were declared extinct in the wild in 1980. But a lack of data makes it challenging to define the species—or, for that matter, to determine whether a private company has cloned the red wolf or something else entirely. Upholt doesn’t deal in simple explanations; the pleasure, here, is in the complexity.
The concept of a “species” is less sturdy than your high school biology teacher might have led you to believe. The most familiar definition is that a species consists of animals that can produce fertile offspring. But that’s a rule various species of canids violate all the time; it’s long been clear that North America’s soup of Canis genes is something less like a family tree and more like a river—one that’s broken by islands and sandbars into many braided channels that split and merge and re-split.
For China Books Review, Zhang Er reflects on growing up in Beijing during the Cultural Revolution, and how she owes her love of reading to Auntie Zou, a librarian who stripped banned books of their covers and any pages marked with the library seal of the Workers’ Club, smuggled them home, and secretly loaned them to her. Even amid the chaos of that era, Er remembers this part of her childhood as magical, a time “where characters sprung from their pages and interwove with each other’s lives,” and she imagined worlds far beyond the one she lived in.
By the time I was 12 or 13, I could read fast enough to finish the weekly book loan in two days, so I had time to spare before returning it to Auntie Zou. By then I had made a good friend, Yu Ping, who loved reading too. Her home was three blocks from mine. I would bicycle to her place and deliver the book to her. Yu Ping would read day and night to finish the book and return it to me before the due date. We would keep the book wrapped in old newspapers, so that we could read in class without getting into trouble, while our teachers repeated the same quotations from Mao, week after week.
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