Thousands of supporters gathered outside Gemelli Hospital in Rome Saturday yelling "Papa!" after Pope Leo XIV was released after surgery to remove a cancerous node in his lung.
The Holy See announced early Saturday he would be leaving to return to the Vatican.
"Following the doctors’ assessment this morning, Pope Leo XIV will be discharged today from Gemelli Hospital, where he was hospitalized for surgery on his right lung," a statement from the Holy See read.
"He will leave the hospital in the early afternoon and return to the Vatican. Tomorrow, he will lead the Angelus prayer from the window of the papal apartment."
The pope received blood tests and a chest X-ray Saturday, both of which confirmed he is well enough to return to the Vatican, according to Vatican News.
Before he departed, Pope Leo reportedly visited the children's oncology ward. While in the hospital, the Pope received letters from some of the children in the ward.
"Pope Leo, our prayers are for you," a girl named Eleonora, who had been receiving treatment in the oncology ward, wrote to him, according to letters released by Vatican News.
"May God, the Most Holy Virgin, and the guardian angels always protect you," she added.
Eleanora's mother told the Pope that she was now healthy, according to the Vatican.
"Faith moves mountains," Eleanora wrote to Pope Leo. "God has heard our prayers."
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Pope Leo underwent thoracic surgery to remove a cancerous node in his lung Tuesday.
After the successful surgery, doctors diagnosed him with lung adenocarcinoma, a form of lung cancer.
"The Pope was in the operating room approximately three hours, while the operation itself lasted about 90 minutes. The doctors said it was successful and there were no complications," a statement from the Holy See press office read.
"Pope Leo awoke normally after surgery and, following a brief period of observation, returned to his room on the hospital’s 10th floor," Vatican News added in a statement.
While recovering, Pope Leo called Russian President Vladimir Putin and urged him to call for a ceasefire in the Ukrainian city of Oleshky.
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"During the conversation, the Holy Father expressed his deep concern about the grave humanitarian situation in the city of Oleshky, in the Kherson region, and called for a ceasefire to allow the delivery of food and medical assistance and the voluntary and safe evacuation of the civilian population," a statement from the Vatican read.
"Finally, the Holy Father reaffirmed the Holy See’s commitment to promoting dialogue and peace."
Russia has controlled the southern Ukrainian city since May and has not allowed any humanitarian food deliveries into the city. Oleshky also has no electricity, gas or running water, and the hospital is barely functional, according to previous Fox News Digital reporting.
Fox News Digital contacted the Holy See for further comment.
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Fox News Digital's Brie Stimson and Fox News' Courtney Walsh-Annesi contributed to this report.
Pope Leo XIV called Russian President Vladimir Putin while recovering from surgery in the hospital to urge him to call a ceasefire in the city of Oleshky in Ukraine.
"During the conversation, the Holy Father expressed his deep concern about the grave humanitarian situation in the city of Oleshky, in the Kherson region, and called for a ceasefire to allow the delivery of food and medical assistance and the voluntary and safe evacuation of the civilian population," the Vatican said in a statement.
"Finally, the Holy Father reaffirmed the Holy See’s commitment to promoting dialogue and peace."
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The situation in Oleshky is dire with no humanitarian food deliveries allowed in the Russian-controlled city since May. It also has no electricity, gas or running water, and the hospital is barely functional.
The pope was diagnosed with lung cancer Tuesday and underwent a procedure to remove the lower lobe of his right lung.
The 71-year-old remained in the hospital recovering on Friday but seemed to be doing well.
Along with the call, he held Mass in a makeshift hospital chapel, and the Vatican released the first images of him since his surgery, which showed him standing at an altar.
POPE LEO XIV SEEN FOR FIRST TIME SINCE LUNG CANCER SURGERY AMID MAJOR RECOVERY MILESTONE
His doctors said he showed "continued improvement."
"His post-operative recovery allows him to carry out his normal daily activities completely on his own," a medical update signed by his personal physician, Luigi Carbone, and the head of thoracic surgery at Gemelli, Dr. Stefano Margaritora, said.
The pope is expected to deliver his traditional Angelus prayer service on Sunday either from the hospital or the Vatican.
He is also still expected to travel to Uruguay, Argentina and Peru starting Nov. 6 as planned.
The Kremlin blames Ukraine for the situation in Oleshky with Putin giving the pope a "detailed explanation regarding the Kyiv regime’s responsibility for the difficult humanitarian situation there," the Kremlin said.
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Putin also supports "the Vatican’s intention to help create conditions for ensuring the safety of the local population and facilitating the delivery of essential supplies," the Kremin added.
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