Pope Leo XIV does not need any further treatment after surgery for lung cancer, the Vatican announced on Wednesday evening.
The Vatican press service said a new biopsy, carried out on tissue removed in the operation, led his doctors to conclude that more therapy is unnecessary.
The 71-year-old pope had the lower lobe of his right lung removed at Rome’s Gemelli Hospital on 13 October.
The Vatican described the operation as successful and free of complications. It followed examinations that found a suspicious nodule.
After the surgery the Vatican said doctors were not considering chemotherapy or other treatment while awaiting further test results.
The pope was expected to remain in hospital for about a week, and his public schedule was cleared until at least 20 October.
Pope Leo XIV will need no further treatment for lung cancer after final tests confirmed the disease was localized, his doctors said Wednesday.
Dr. Luigi Carbone and Professor Stefano Margaritora announced the findings just over a week after surgeons removed a tumor from the pontiff’s right lung.
"The final histopathology and molecular testing reports on the tissue removed during the Holy Father’s surgery were issued today," the doctors said in a statement.
"The results confirmed that the tumor was a lung adenocarcinoma and that the disease was localized. A subsequent oncological assessment has confirmed that no further treatment is necessary."
Pope Leo underwent surgery Oct. 13 at Rome’s Gemelli Hospital. The operation lasted about 90 minutes, with the pope spending approximately three hours in the operating room, according to the Holy See.
"The doctors said it was successful and there were no complications," the Holy See press office said after the procedure.
The pontiff awoke normally and returned to his hospital room following a brief observation period, Vatican News reported.
He was discharged Saturday after blood tests and a chest X-ray confirmed he was well enough to return to the Vatican. Thousands of supporters gathered outside the hospital, shouting "Papa!" as he departed.
Before leaving, Leo visited the children’s oncology ward, where young patients had sent him letters during his hospital stay.
Pope Leo XIV is back at work. A clearly delighted pontiff returned to St. Peter's Square on Wednesday, waving to Vatican pilgrims and blessing babies from his open-air popemobile as his first general audience began since undergoing lung cancer surgery just over one week ago.
European Parliament Vice President Pina Picierno has announced a hunger strike to draw international attention to the humanitarian disaster in Russian-occupied Oleshky in Ukraine’s Kherson Oblast, she wrote on X on 20 October. The Italian lawmaker called on associations, citizens, and institutions to join her and demand a humanitarian truce, food and medicine for residents, and safe evacuation for those who want to leave.
Russia has occupied the left bank of the Dnipro in Kherson Oblast since 2022. Its forces have cut Oleshky off, leaving its remaining residents short of food and medicine, Ukrainian officials and UN monitors say. Oleshky had about 24,000 residents before the full-scale invasion. About 1,700 remain, including 47 children, Danielle Bell, head of the UN Human Rights Monitoring Mission in Ukraine, said. Picierno’s protest adds to growing international pressure after Pope Leo XIV asked Russian leader Vladimir Putin for a truce to help the town.
“This battle cannot be mine alone”
In Oleshky, thousands of people are trapped in territory occupied by the Russian army, without regular access to food and medicine, Picierno wrote. Mined areas make escape extremely dangerous, she added.
“Those who stay risk dying of hunger, those who try to leave risk their lives,” she wrote. “To draw international attention to this emergency, I have announced a hunger strike. But this battle cannot be mine alone.”
She said the campaign is meant to support the efforts of Pope Leo XIV and others trying to avert a humanitarian tragedy. By the morning of 21 October, 277 people had joined the initiative, Liga reported.
Drones carry food packages across the Dnipro to starving residents of Russian-occupied Oleshky, Kherson Oblast, September 2026. Screenshot: Kherson Oblast Military Administration via Telegram
Picierno, who left Italy’s Democratic Party in June and joined the Renew Europe group, has backed military aid to Ukraine, tougher sanctions on Russia, and Ukraine’s bid to join the EU, according to Liga.
A town Kyiv calls a “death trap”
On 16 October, Pope Leo XIV expressed deep concern to Putin about the situation in Oleshky. He asked for a truce so that food and medical aid could be delivered and civilians could leave voluntarily and safely.
Oleshky, Kherson Oblast, has been under Russian occupation since 2022, following Russia’s capture of the city during the initial phase of its full-scale invasion of Ukraine. Photo: Dmytro Lubinets
A day later, Ukraine’s Foreign Minister Andrii Sybiha urged the UN and the International Committee of the Red Cross to help evacuate residents.
“Russians are trying to turn the Ukrainian town of Oleshky into a death trap,” Sybiha wrote. “Dozens of bodies lie in the streets or in homes, as Russians forbid residents from burying them.”
Ukraine has flown tons of food into the town by drone. Russian troops seize some of the parcels and accuse the people who receive them of cooperating with Ukraine, local officials say. A resident said eggs there cost nearly 20 times the US price.
Explore further
Russia holds 2,000 people hostage in Oleshky without food or water—Ukraine flew 4,000 kg of food to locals across the Dnipro
Evacuation talks “moved forward”
Talks with Russia on a ceasefire and evacuation are at the stage of “agreeing the final details,” Ukraine’s human rights ombudsman Dmytro Lubinets said on 18 October. He estimated that about 6,000 civilians, including up to 200 children, remain in Oleshky and six nearby settlements. He gave no timeline.
On 20 October, President of Ukraine Volodymyr Zelenskyy said Ukraine was doing everything it could to help people in Oleshky, calling the situation there “simply terrible.”
The conversation with Zelensky comes three days after the pope spoke with Russian President Vladimir Putin to call for a ceasefire to evacuate civilians from the front-line town.
Pope Leo XIV thanked thousands of faithful in St. Peter's Square on Sunday for their prayers while he was hospitalized for an operation to remove a malignant tumor, and said he plans to gradually return to his usual duties.
Hollywood A-list actor Chris Pratt has joined Pope Leo XIV as co-star in a documentary that trawls the history, religious passion and archaeological discoveries enveloping the tomb of St. Peter at the Vatican.
Pope Leo XIV made a remarkable return to the Vatican on Sunday, appearing before thousands of Catholic faithful in St. Peter's Square just five days after undergoing surgery to remove a cancerous tumor from his lung.
The 71-year-old pontiff delivered his traditional Angelus prayer from a window overlooking the square, marking his first official engagement since being discharged Saturday from Rome's Gemelli hospital, where doctors removed the lower lobe of his right lung.
Leo thanked the faithful for their prayers and support throughout his hospitalization, saying his recent health struggles had brought him closer to those suffering from illness. He also expressed gratitude to the doctors, nurses and hospital staff who cared for him following the operation.
The first American-born pope said he planned to gradually resume his regular activities with God's help and the continued prayers of the faithful.
During his Angelus address, Leo reflected on one of Jesus' best-known teachings, "Give therefore to the emperor the things that are the emperor's, and to God the things that are God's," urging Christians to live with integrity and resist hypocrisy.
His return came sooner than expected after doctors initially anticipated a hospital stay of approximately one week following Tuesday's surgery.
As he departed the hospital on Saturday, the pope told a reporter in English that he was doing "much better."
Claire Holland, visiting from Jacksonville, Fla., told The Associated Press she felt "very blessed" to witness the pope's return.
"I think there have been millions and millions of prayers. And he is a strong determined man, and I am so happy that he is feeling well enough to do this," Holland said.
The surgery marked the first major health crisis of Leo's 17-month pontificate. Doctors confirmed that the tumor was adenocarcinoma, the most common form of lung cancer.
Doctors are conducting further testing on the tumor and surrounding lymph nodes to determine the extent of the disease and whether additional treatment, including chemotherapy, immunotherapy or targeted therapy, may be necessary.
The pope is scheduled to visit Uruguay, Argentina and Peru from Nov. 6 through Nov. 17, a demanding itinerary that includes a dozen flights and two helicopter rides to high-altitude destinations.
His surgeon, Dr. Stefano Margaritora, told Vatican News on Saturday that the pope appears well enough to go on the trip.
"The Holy Father has put his heart and soul into his recovery," Margaritora said, adding that he expected Leo to recover fully from the surgery "in another 10 days or so."
"As for a long trip involving air travel in about three weeks, I would say there are no clinical reasons why it should not take place," Margaritora said.
Fox News’ Courtney Walsh and The Associated Press contributed to this report.
Thousands of supporters gathered outside Gemelli Hospital in Rome Saturday yelling "Papa!" after Pope Leo XIV was released after surgery to remove a cancerous node in his lung.
The Holy See announced early Saturday he would be leaving to return to the Vatican.
"Following the doctors’ assessment this morning, Pope Leo XIV will be discharged today from Gemelli Hospital, where he was hospitalized for surgery on his right lung," a statement from the Holy See read.
"He will leave the hospital in the early afternoon and return to the Vatican. Tomorrow, he will lead the Angelus prayer from the window of the papal apartment."
The pope received blood tests and a chest X-ray Saturday, both of which confirmed he is well enough to return to the Vatican, according to Vatican News.
Before he departed, Pope Leo reportedly visited the children's oncology ward. While in the hospital, the Pope received letters from some of the children in the ward.
"Pope Leo, our prayers are for you," a girl named Eleonora, who had been receiving treatment in the oncology ward, wrote to him, according to letters released by Vatican News.
"May God, the Most Holy Virgin, and the guardian angels always protect you," she added.
Eleanora's mother told the Pope that she was now healthy, according to the Vatican.
"Faith moves mountains," Eleanora wrote to Pope Leo. "God has heard our prayers."
After the successful surgery, doctors diagnosed him with lung adenocarcinoma, a form of lung cancer.
"The Pope was in the operating room approximately three hours, while the operation itself lasted about 90 minutes. The doctors said it was successful and there were no complications," a statement from the Holy See press office read.
"Pope Leo awoke normally after surgery and, following a brief period of observation, returned to his room on the hospital’s 10th floor," Vatican News added in a statement.
While recovering, Pope Leo called Russian President Vladimir Putin and urged him to call for a ceasefire in the Ukrainian city of Oleshky.
"During the conversation, the Holy Father expressed his deep concern about the grave humanitarian situation in the city of Oleshky, in the Kherson region, and called for a ceasefire to allow the delivery of food and medical assistance and the voluntary and safe evacuation of the civilian population," a statement from the Vatican read.
"Finally, the Holy Father reaffirmed the Holy See’s commitment to promoting dialogue and peace."
Russia has controlled the southern Ukrainian city since May and has not allowed any humanitarian food deliveries into the city. Oleshky also has no electricity, gas or running water, and the hospital is barely functional, according to previous Fox News Digital reporting.
Fox News Digital contacted the Holy See for further comment.
Pope Leo XIV called Russian President Vladimir Putin while recovering from surgery in the hospital to urge him to call a ceasefire in the city of Oleshky in Ukraine.
"During the conversation, the Holy Father expressed his deep concern about the grave humanitarian situation in the city of Oleshky, in the Kherson region, and called for a ceasefire to allow the delivery of food and medical assistance and the voluntary and safe evacuation of the civilian population," the Vatican said in a statement.
"Finally, the Holy Father reaffirmed the Holy See’s commitment to promoting dialogue and peace."
The situation in Oleshky is dire with no humanitarian food deliveries allowed in the Russian-controlled city since May. It also has no electricity, gas or running water, and the hospital is barely functional.
The pope was diagnosed with lung cancer Tuesday and underwent a procedure to remove the lower lobe of his right lung.
The 71-year-old remained in the hospital recovering on Friday but seemed to be doing well.
Along with the call, he held Mass in a makeshift hospital chapel, and the Vatican released the first images of him since his surgery, which showed him standing at an altar.
His doctors said he showed "continued improvement."
"His post-operative recovery allows him to carry out his normal daily activities completely on his own," a medical update signed by his personal physician, Luigi Carbone, and the head of thoracic surgery at Gemelli, Dr. Stefano Margaritora, said.
The pope is expected to deliver his traditional Angelus prayer service on Sunday either from the hospital or the Vatican.
He is also still expected to travel to Uruguay, Argentina and Peru starting Nov. 6 as planned.
The Kremlin blames Ukraine for the situation in Oleshky with Putin giving the pope a "detailed explanation regarding the Kyiv regime’s responsibility for the difficult humanitarian situation there," the Kremlin said.
Putin also supports "the Vatican’s intention to help create conditions for ensuring the safety of the local population and facilitating the delivery of essential supplies," the Kremin added.
Pontiff is recovering from a lobectomy, which is standard treatment for lung cancer caught early and can be curative
On Tuesday, surgeons in Rome removed the lower part of Pope Leo’s right lung, after a routine health check found a small growth that tests have since confirmed as lung cancer. The operation, called a lobectomy, is the standard treatment for lung cancer caught early, and for many patients it is the only treatment they will ever need. So what exactly did his doctors do, and what happens next?
Worshippers are attending mass and praying for Pope Leo XIV's recovery after doctors removed cancerous tissue on 13 October. The 71-year-old pontiff was diagnosed with lung cancer before undergoing an operation. The Vatican has reported his recovery is progressing as expected and the pope has thanked well-wishers for their prayers
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