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Ébola. Novo ensaio vai testar vacinas contra Bundibugyo

Oxford e Moderna já têm vacinas em fase avançada. SAGE alerta para urgência de aprovação regulatória enquanto letalidade no Congo chega aos 48,3%.

© WHO HANDOUT/EPA

O vírus Ébola transmite-se por contacto direto com fluidos corporais de pessoas ou animais infetados e provoca febre hemorrágica grave, vómitos, diarreia e hemorragias internas
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DR Congo’s deadliest Ebola outbreak kills over 4,200 as armed groups undermine response

In less than five months, the fastest-spreading Ebola outbreak in world history has killed at least 4,205 people in the conflict-ridden eastern region of the Democratic Republic of Congo (DRC) as of October 7.

It is the deadliest outbreak in the DRC since the disease was first discovered in the country in 1976, killing nearly one in two of the 8,728 people confirmed to be infected.

With treatment still in experimental stages, there is no specifically approved treatment for the particular Bundibugyo strain of the Ebola virus that caused this outbreak, declared on May 15. 

However, the virus had been circulating in communities in Ituri province since mid-February, three months before the outbreak was identified and officially declared.​

Aid cuts: unpaid frontline workers

When the health response started, already late, it was severely underfunded, as the UK, France and Germany have also followed in the footsteps of the US to slash humanitarian aid and increase military spending.​

The UN Office for the Coordination of Humanitarian Affairs (OCHA) said in late September that the Humanitarian Response Plan had only half the funding needed to counter the outbreak.​

Contact tracing is well below the Africa Centers for Disease Control and Prevention (CDC) and the WHO-recommended 95% to effectively break transmission. Only now in October, it has been built up to 80.4%, which still means that almost 20% of the people at risk of exposure to the virus due to contact with confirmed cases are off the radar of the health authorities, and could potentially be transmitting the disease further.

Lack of funds has meant that the understaffed and overworked frontline health workers – scores of whom have died in the line of duty – have been repeatedly forced to go on strike to protest unpaid wages. Their efforts are further impeded by the poor transport infrastructure and lack of healthcare facilities in the remote eastern region where the disease is spreading.​

Armed conflict complicating health response 

Armed conflict displacing millions on this mineral-rich land is another major hurdle in the way of effective health response. In Ituri, the epicenter of the outbreak, a key Ebola transit center in the fighting-affected Kigonze camp burnt down on September 29.​

The camp, which had housed 19,000 Internally Displaced People (IDPs) fleeing violence, was reportedly infiltrated by the Convention for the Popular Revolution (CRP).

Uganda​

This coalition of armed militias, formed in March 2025 at a hotel in Uganda’s capital, Kampala, is led by Thomas Lubanga, a former warlord, convicted by the International Criminal Court (ICC) of war crimes, released from prison in 2020 after serving 14 years. He resides in Uganda, where he is also known to have recruited fighters along ethnic lines.​

In a 2022 judgment, the International Court of Justice (ICJ) ordered Uganda to pay DRC USD 325 million in reparations. This included USD 225 million for killings, rapes, child soldier recruitment, and displacement, USD 40 million for damage to property, and USD 60 million for plundering its gold, diamonds, and timber as an “occupying power” in Ituri from 1998 to 2003.​

The nature of the occupation has since evolved. Under a bilateral agreement with the DRC, Uganda had deployed 2,000 troops to the country to jointly fight an Islamic State-affiliated group. However, Uganda deployed an additional 4,000 troops without the DRC’s consent in early 2025, around the time as the CRP’s formation in Kampala.  ​

Searching for CRP militants and weapons, soldiers and police entered the camp on September 20. When they came under fire, clashes erupted between the security forces and the militants. Thousands of IDPs fled again as gunfire continued rattling around the camp for days. Deaths, injuries, and arrests were reported.​

Ebola transit center burns down

Amid this violence, on September 29, fire engulfed the camp’s Ebola transit center. It is a facility for the isolation and care of suspected cases, until the results of the lab tests on their blood samples. If confirmed as positive, they are then transported to an Ebola treatment center.​

“It’s been a huge struggle to create Ebola transit centers [and] Ebola treatment centers; it’s required money, bringing in staff and it’s been a struggle all across the east. So, when we lose a center, that means we lose capacity, we lose investment and we have to start again,” said Julien Harneis, UN’s senior Ebola response official in the DRC.​

“Eastern DRC now faces a catastrophic collision of disease and conflict, with the Ebola outbreak in Ituri province outpacing the response,” the WHO’s director general, Tedros Ghebreyesus, had warned in May.​

The outbreak has since reached seven of DRC’s 26 provinces, predominantly in the east. About three-quarters of the confirmed cases remain concentrated in Ituri. However, its neighboring province, North Kivu, which has another 20% of confirmed cases, is emerging as the new hotspot.​

Rwanda

Large areas of this province are occupied by Rwandan troops and its proxy militias, the M23, which captured its capital, Goma, in January 2025, and went on to expand territorial control into South Kivu province.

​Without humanitarian access to these occupied areas, the government cannot mount a health response, Communications Minister Patrick Katembwe said in late May, second week after the outbreak was declared. He called for the “withdrawal of foreign forces and the removal of their auxiliaries.”

Instead, the M23’s parallel administration launched a separate health response in the areas under its control, independently of the DRC government, with which cooperation was limited to data sharing and lab testing. This severely hampered contact tracing, especially because people regularly travel between the M23-held areas and government-controlled territory.

“Multiple outbreaks are developing at the same time”

​The parallel M23 administration has also meant additional delays in diagnosis. With bed capacity in Ebola treatment centers stretched taut in North Kivu, medics in this province are forced to refer infected patients to general health facilities, where a third of all confirmed cases are being treated, posing further risk of transmission into the wider community.

​The spread has rapidly increased since September in this province, which now accounts for nearly 40% of all new confirmed cases, up from 24% in August-end, Doctors Without Borders (MSF) said on October 5.

​“It is like fighting a megafire,” said Stéphanie Hoffmann, MSF coordinator of the treatment center in Butembo, a major commercial city in the province. “Multiple outbreaks are developing at the same time, with varying intensity and in different locations. As long as new hotspots continue to emerge while the virus spreads across northern North Kivu, containing the epidemic will remain extremely difficult.”

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Ébola na RDCongo chega a 4.381 mortos e mais de 9.000 casos

Com taxa de letalidade de 48,3%, esta é já a segunda epidemia de ébola mais mortífera da história. A estirpe de Bundibugyo não tem tratamento, mas há duas vacinas em ensaios.

© STRINGER/EPA

epidemia é a segunda mais mortífera da história a nível global, embora ainda esteja longe da mais grave, que causou cerca de 11 mil mortes na África Ocidental entre 2014 e 2016
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Kongo et Angola. 1650-1750. Une rencontre en images

JPEG - 20 kio

Les centaines de textes, dessins et gravures qui illustrent cet ouvrage lèvent le voile sur un pan méconnu de l'histoire de l'Afrique précoloniale. En 1645, des capucins franciscains abordent l'embouchure du fleuve Congo, afin d'évangéliser les populations du royaume du Kongo et de l'Angola. Ils multiplient les écrits, riches de très nombreuses images destinées à la hiérarchie papale et à l'instruction des futurs frères. Cécile Fromont, professeure d'histoire de l'art et d'architecture à Harvard, interroge ce « corpus visuel capucin » en le reliant aux contextes culturel, social et politique des peuples concernés. Elle note que l'enjeu central des capucins consistait à « extirper de cette région ce qu'ils jugeaient être de l'idolâtrie ». Certaines aquarelles montrent des scènes pacifiques et d'autres d'une extrême violence. L'historienne insiste sur le « processus de création transculturelle » qui fut mis en œuvre, les missionnaires ayant développé des échanges avec les érudits africains.

Voir en ligne : /2026/10/PIOT/70073

CNRS Éditions, Paris, 2026, 254 pages, 39 euros.

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Several arrested in protests against constitutional changes in DRC

Protests rocked the Democratic Republic of Congo on Tuesday, September 15, as opposition supporters took to the streets in Kinshasa and several other cities to oppose proposed constitutional changes that they say could allow President Félix Tshisekedi to seek a third term.

The demonstrations were called by the opposition coalition C64 (Coalition Article 64), which has campaigned against changes to the Constitution and what it considers an attempt to remove the existing two-term presidential limit.

The demonstrations were also reported in several cities. In Kinshasa, hundreds of protesters gathered around the Limete area before the march was disrupted by clashes involving demonstrators and people identified as members of the Force du Progrès, a group affiliated with Tshisekedi’s ruling UDPS party. Police used tear gas and warning shots to disperse the crowd. At least 10 people were arrested in Kinshasa.

Opposition accuses authorities of an “ambush”

Martin Fayulu, leader of the Engagement for Citizenship and Development (ECiDé) and a leading C64 figure, accused authorities of deliberately allowing pro-government militants to attack the opposition march.

In a post following the confrontation, Fayulu said the C64 had agreed on its route with Kinshasa’s city authorities before the march. He alleged that protesters were then confronted in Limete by armed members of the Force du Progrès while police used tear gas against the marchers.

Fayulu wrote that the C64 had been “the victim of an ambush” and accused the authorities of using a political militia alongside security forces. He called on Kinshasa’s city authorities and the national government to explain what happened.

Read more: Lithium mining in the DRC: A new mineral rush spearheaded by the US, EU, and other major powers

The confrontation prevented the C64 march from reaching its planned destination and from delivering its memorandum to the authorities at the People’s Palace.

Opposition resistance has been building 

Tuesday’s demonstrations were the latest escalation in an opposition campaign that has been building since June, when there were protests after Congo’s parliament approved legislation allowing constitutional amendments to be submitted to a referendum.

The National Assembly and Senate have both backed the referendum legislation. Critics argue that the process could eventually open the way for amendments to the presidential term-limit provisions.

Tshisekedi was first elected president in 2018 and re-elected in 2023. Under the current Constitution, the president serves a maximum of two five-year terms. His current term runs until 2028.

The proposed constitutional changes have therefore become a major point of confrontation between the government and opposition. The C64 says it is defending the existing constitutional order and has rejected any change that could enable Tshisekedi to seek another term.

The protests and the crisis is happening as the government faces other major challenges, including conflict in eastern Congo and an Ebola outbreak.

Read more: Ebola spreads to 60 health zones in eastern DRC; UN warns of funding shortfall

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