Marco Rubio has brought nearly 300 American business representatives to Uzbekistan for a meeting with representatives of the five states of Central Asia. But Daniel N. Rosenblum, a former US ambassador to Uzbekistan and Kazakhstan, cautions that investment faces major obstacles.

Ukrainian Foreign Minister Andriy Sybiha said that US President Donald Trump's decision to waive sweeping sanctions against Russia was "indecisiveness," which "sends the wrong message to the aggressor."

As Secretary of State Marco Rubio heads to Uzbekistan, Washington is hoping the high-level diplomatic engagement translates into concrete economic and security cooperation. 

US Secretary of State Marco Rubio heads to Uzbekistan this weekend for talks with five Central Asian countries as the Trump administration seeks to strengthen commercial ties and expand Washington's strategic presence in the region.

Central Asian nations are increasingly turning to India, China, Turkey, and Europe for military equipment to reduce their dependence on Russia. Analysts note that this diversification offers greater political flexibility but could create long-term logistical and operational challenges.

Ukrainian drugmakers could lose the certificates that let them sell in Uzbekistan, their most important export market, Ukrainian business outlet Ekonomichna Pravda reported on 7 October. Uzbekistan is ending remote factory inspections next year, and industry sources say its inspectors are wary of traveling to a country at war.

Russia's war keeps reshaping Central Asia's trade with both warring countries: Ukrainian refinery strikes pushed Russian fuel shortages into the region, and Kazakhstan gained leverage over a Russian retail giant.

A market worth a third of export earnings

Uzbekistan brings in about 30% of the Ukrainian drug industry's foreign-currency earnings, and one in 10 medicine packs sold there is Ukrainian, Ekonomichna Pravda wrote. By the outlet's count, at least three of Ukraine's five biggest drugmakers by revenue rank it as their top foreign market.

The currency from Uzbekistan lets manufacturers keep prices low in Ukraine and absorb losses from Russian strikes, three industry sources told Ekonomichna Pravda. Losing the market would force producers to raise domestic prices or pull low-margin medicines, which "will hit the Ukrainian patient," said Hennadii Vovk, former deputy head of Ukraine's State Service on Medicines and Drug Control.

Exports reached $114 million in January–June 2026, more than in all of 2021, said Yevheniia Piddubna, government relations head at Farmak, Ukraine's largest drugmaker. She said Uzbekistan takes 35% of Farmak's exports.

Data from the YouControl business registry, cited by the outlet, complicates that picture. In 2022, 30–35% of Farmak's products went to Uzbekistan. In 2025, Uzbekistan was not among its direct buyers. Farmak explained that wartime currency rules cap payment terms at 180 days, while foreign buyers often demand longer. So part of its trade runs through the group's Polish company.

Remote checks end, and inspectors hesitate to travel

Uzbekistan grants three-year certificates of good manufacturing practice (GMP) after inspecting the factory. Since the pandemic, it has allowed remote checks. That suited Ukraine, where Uzbek experts avoided traveling because of Russia's invasion, industry sources told the outlet. Remote inspections end on 1 January 2027.

Most Ukrainian certificates expire within a year. Farmak's runs out in November 2026, and the company may not manage to renew it in time. Three producers renewed under the old rules until 2029: Darnytsia, the Borshchahivskyi Chemical and Pharmaceutical Plant, and Farmex Group. According to Piddubna, Uzbekistan's regulator has drafted rules for remote inspections in force-majeure cases, but nothing has been put into practice. Industry sources said the Uzbek Presidential Administration must sign off.

Producers have asked the Office of the President, the Foreign Ministry, and the Health Ministry to raise the issue with Uzbekistan's government, but no Ukrainian experts have been sent there yet, the outlet reported. Russia, whose share of the Uzbek drug market is almost the same as Ukraine's, is ready to take Ukraine's place, its sources said.

Kazakhstan has asked Moscow to help bring home citizens who say they were pressured into signing military contracts to fight in Ukraine. The request puts a fresh spotlight on the vulnerability of Central Asian migrants to Russia’s military enlistment efforts.

The Lenin District Court in Bishkek found activist and politician Mavlyan Askarbekov guilty and sentenced to two years in prison on offenses related to a law on incitement of racial, ethnic, national, religious, or interregional hatred, a verdict he called "absurd."

Three of the four Afghans who left their country to compete last week in the Chess Olympiad in Samarkand, Uzbekistan, were detained at the border on Monday when they returned to Afghanistan, where chess is banned by the Taliban government. The players are under house arrest in Kabul and face penalties that could include corporal punishment. The fourth player has been able to return home without reprisals.

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Kyrgyzstan is set to send a domestically produced satellite into orbit on October 1, marking the Central Asian state's first feat of spacefaring. Uzbekistan has announced its own plans for a domestic satellite.

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